Out of Stock! Due to unexpected
manufacturing delays, we do not expect to have our Mighty E-Full Spectrum back in
stock until Fall, 2012.
Mighty E-Full Spectrum™ is a full spectrum mixed tocopherol, dry vitamin E in which the tocopherols are present in their unesterified form.* Being a Full Spectrum, Dry Vitamin E, Mighty E-Full Spectrum™ consists of a mixture of all 8 variants of vitamin e: the 4 natural tocopherols: d-alpha tocopherol, d-beta-tocopherol, d-gamma-tocopherol and d-delta tocopherol along with all 4 of the tocotrienols: d-alpha tocotrienol, d-beta-tocotrienol, d-gama-tocotrienol and d-delta tocotrienol. Mighty E-Full Spectrum™ also inncludes alpha-tocopherol as a succinate or dry vitamin E because the succinate variety has been show to have superior absorption and utilization over the oil based alpha-tocopherol vitamin e supplements.* Mighty E-Full Spectrum™ also has the addition of Pancreatin to further help increase absorption and utilization.* The superior absorption found in Mighty E-Full Spectrum™, means you can get all the great benefits associated with Vitamin E with fewer capsules: Instead of taking 6 to 8 of the oil based equivalently measured vitamin e's, with Mighty E-Full Spectrum™ you only need 1 or 2 capsules per day.
Technically speaking, the term vitamin E describes a family of eight antioxidants: four tocopherols (alpha-, beta-, gamma-, and delta-) and four tocotrienols (alpha-, beta-, gamma-, and delta-). Most vitamin e supplements only contain 1 to 4 out of the full 8 antioxidants.* Most if not all vitamin e supplements, contain Alpha-tocopherol because it is the only form of vitamin E that is actively maintained in the human body; therefore, it is the form of vitamin E found in the largest quantities in blood and tissues[1].* Alpha-tocopherol is also the only form that meets the latest Recommended Dietary Allowance (RDA) for vitamin E.
Mighty E-Full Spectrum™ is a full spectrum mixed tocopherol, dry vitamin E in which the tocopherols are present in their unesterified form.
D-Alpha-Tocopherol [Succinate]
According to the textbooks: "Alpha-tocopherol is the form of vitamin E that is preferentially absorbed and accumulated in humans.*[2]" In other words, this the form of vitamin E the body prefers to absorb and store. The measurement of "vitamin e" activity is international units (IU). This method was adopted as it was based on fertility enhancement by the prevention of spontaneous abortions in pregnant rats relative to alpha-tocopherol.*
The succinate variety of d-alpha-tocopherol, as it is found in Mighty E-Full Spectrum™, does not require an oil to be absorbable as it is water-dispersible/absorbable. And, because no oils are needed as carriers to ensure absorbability it is therefore not added to the product, further ensuring the product is unesterified or de-esterified.
Tocopherols: Alpha, Beta, Gamma and Delta
Tocopherols (or TCP) are a class of chemical compounds of which many have vitamin E activity*. It is a series of organic compounds consisting of various methylated phenols.* First identified in 1936 from a dietary fertility factor in rats, it was given the name "tocopherol" from the Greek words “τοκος” [birth], and “φορειν”, [to bear or carry] meaning in sum "to carry a pregnancy," with the ending "-ol" signifying its status as a chemical alcohol.*
Tocotrienols: Alpha, Beta, Gamma and Delta
Tocotrienols are natural compounds found in select vegetable oils, wheat germ, barley, saw palmetto, and certain types of nuts and grains. This variant of vitamin E only occurs at very low levels in nature, with the highest concentration found in palm oil.[4]
Since the 1980s, there have been more studies proving tocotrienols are more potent in their anti-oxidation[5]... effect[6][7] than the common forms of tocopherol due to its chemical structure*. The unsaturated side-chain in tocotrienols makes them penetrate tissues with saturated fatty layers more efficiently,[8] making them ideal for anti-aging oral supplements[9] and skin care range.*[10]
Vitamin E has long been known for its antioxidative properties against lipid peroxidation in biological membranes and alpha-tocopherol is considered to be the most active form.* However, since 2000, scientists have suggested tocotrienols are better antioxidants than tocopherols[11][12] at protecting the heart and keeping it healthy.*[13]
Linus Pauling Institute Recommendation
Scientists at the Linus Pauling Institute feel there exists credible
evidence that taking a supplement of 200 IU (134 mg) of natural source
d-alpha-tocopherol (RRR-alpha-tocopherol) daily with a meal may help
protect adults from various chronic conditions, such as heart disease,
stroke, neurodegenerative diseases, and some types of cancer. The
amount of alpha-tocopherol required for such beneficial effects appears
to be much greater than that which could be achieved through diet
alone.[3]***
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References:
1. Traber MG. Utilization of vitamin E. Biofactors. 1999;10(2-3):115-120. (PubMed)
2. Rigotti A (2007). "Absorption, transport, and tissue delivery of vitamin E". Mol. Aspects Med. 28 (5-6): 423–36. doi:10.1016/j.mam.2007.01.002. PMID 17320165.
3. Higdon, PhD, Jane. Vitamine E. 2004. (lpi.oregonstate.edu)
4. Vitamin E in health and disease.By Lester Packer, Jürgen Fuchs, 1993
5. Serbinova, E; Kagan; Han; Packer (1991). "Free radical recycling and intramembrane mobility in the antioxidant properties of alpha-tocopherol and alpha-tocotrienol" (Free full text). Free radical biology & medicine 10 (5): 263–75. doi:10.1016/0891-5849(91)90033-Y. ISSN 0891-5849. PMID 1649783.
6. Constantinou, C; Papas; Constantinou (Aug 2008). "Vitamin E and cancer: An insight into the anticancer activities of vitamin E isomers and analogs". International journal of cancer. Journal international du cancer 123 (4): 739–52. doi:10.1002/ijc.23689. ISSN 0020-7136. PMID 18512238.
7. Wada, S (2009). "Chemoprevention of tocotrienols: the mechanism of antiproliferative effects". Forum of nutrition 61: 204–16. doi:10.1159/000212752. ISSN 1660-0347. PMID 19367124.
8. Suzuki, YJ; Tsuchiya; Wassall; Choo; Govil; Kagan; Packer (Oct 1993). "Structural and dynamic membrane properties of alpha-tocopherol and alpha-tocotrienol: implication to the molecular mechanism of their antioxidant potency". Biochemistry 32 (40): 10692–9. doi:10.1021/bi00091a020. ISSN 0006-2960. PMID 8399214.
9. Rona, C; Vailati; Berardesca (Jan 2004). "The cosmetic treatment of wrinkles". Journal of cosmetic dermatology 3 (1): 26–34. doi:10.1111/j.1473-2130.2004.00054.x. ISSN 1473-2130. PMID 17163944.
10. Traber, MG; Rallis; Podda; Weber; Maibach; Packer (Jan 1998). "Penetration and distribution of alpha-tocopherol, alpha- or gamma-tocotrienols applied individually onto murine skin". Lipids 33 (1): 87–91. doi:10.1007/s11745-998-0183-0. ISSN 0024-4201. PMID 9470177.
11. Yoshida, Y; Niki; Noguchi (Mar 2003). "Comparative study on the action of tocopherols and tocotrienols as antioxidant: chemical and physical effects". Chemistry and physics of lipids 123 (1): 63–75. doi:10.1016/S0009-3084(02)00164-0. ISSN 0009-3084. PMID 12637165.
12. Schaffer, S; Müller; Eckert (01 Feb 2005). "Tocotrienols: constitutional effects in aging and disease" (Free full text). The Journal of nutrition 135 (2): 151–4. ISSN 0022-3166. PMID 15671205.
13. Pruthi, S; Allison; Hensrud (Nov 2001). "Vitamin E supplementation in the prevention of coronary heart disease". Mayo Clinic proceedings. Mayo Clinic 76 (11): 1131–6. doi:10.4065/76.11.1131. ISSN 0025-6196. PMID 11702901.